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We therefore reasoned that, if this hypothesis is correct, addition of exogenous ANG to serum-free medium should be able to restore cell viability.
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In particular, Figure 7B is of importance because if the model is correct the addition of PGRP-SA to alt mutants should restore survival.
The mean percentages of correct additions in the four experimental conditions are reported in the top portion of Table 1.
14C concentrations of samples with lower CFCs were measured, and corrected for addition of 14C-free dissolved inorganic carbon.
Temperature data has been corrected by addition of difference between mean monthly observed temperature and SDSM simulated mean monthly temperature for observed period.
Our previous report indicated that the in vitro proliferative defect of CD4, but not CD8 T cells from HIV-infected donors could be corrected by addition of 1mT [32], which is in apparent contrast with the IDO effect on both CD4 and CD8 T cells that we described here.
These data suggest that inhibition is not directly on the components of the synthesis pathway, since prior studies have shown that defects in NeuB or NeuC, critical synthesis enzymes encoded in Region II (Figure 1A), can be corrected by addition of exogenous precursor sialic acid [34], [35].
The blank was corrected by addition of a 0.5% TBA solution in 10% trichloroacetic acid.
The added value of DWI is illustrated in Fig. 3, in which a false positive finding on T2-weighted MRI was corrected after addition of DWI.
Thus, the next learning step (Phase 2) begins with a deficiency that must somehow be corrected by addition of cost and time (more dose arms and larger enrollment, adaptive study designs, etc)., thereby decreasing efficiency.
Trends in percentage of correct matches with addition of one to three hexose or deoxsugars, or substitution of one to three glycosylation sites, within hypothetical linear or cyclic nonribosomal peptides (a), polyketides (b), or hybrid natural products (c).
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