Sentence examples for cornerstone drug from inspiring English sources

Isoniazid is the cornerstone drug used throughout the course of non-MDR-TB treatment.

Further studies are required to gauge whether tenofovir, which has become a valuable cornerstone drug in treating HIV infection, can also be safely and effectively used as a vaginal or rectal microbicide.

Interestingly, the anti-inflammatory action of MTX, the cornerstone drug for the treatment of rheumatoid arthritis and other inflammatory diseases [ 36], depends on the extracellular conversion of adenine nucleotides to adenosine [ 17].

PZA is one of the cornerstone drugs retained in the treatment of MDR-TB.

Glucocorticoids (GCs) are still the cornerstone drugs used in treatment protocols of a wide range of inflammatory and immune disorders.

One of the cornerstone drugs for both intensification and maintenance therapy is the thiopurine agent 6-mercaptopurine (6-MP) [ 2].

Pyrazinamide (PZA) is an important first-line anti-tuberculosis (anti-TB) drug that is used in short-course chemotherapy and is one of the cornerstone drugs in the treatment of MDRTB (5).

This is a cornerstone of drug discovery, as it means that successive small changes to the structure of an active should retain biological activity against a target.

Much progress has been made in RA treatment in the last decades with methotrexate the cornerstone antirheumatic drug [ 1, 2].

Sulfonylureas and metformin have been the cornerstone of drug therapy for type 2 diabetes, either alone or in combination, for a quarter of a century (22).

Randomized clinical trials (RCTs) are the optimal study design to establish the efficacy of therapeutic or preventive interventions, and are a cornerstone in drug development and comparative effectiveness research.