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Since netpyne is implemented as parallel NEURON code you can use mpi straight away to run parallel simulations, either in computers with multiple cores or large HPCs/supercomputers (e.g. see NSG -- www.nsgportal.org).org
The heterogeneity, high permeability cores, or large record interval etc. may lead the breakthrough time difficult to identify.
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Interestingly, in early studies on PNIPAM encapsulating, multiple magnetic cores or on large PNIPAM-gel particles coated with magnetic particles the hydrodynamic diameter was measured to decrease with increased temperature.
Transcriptomic systems are continually updating which is why most laboratories use their institution's core services or large service providers such as the Broad Institute rather than investing in their own instruments.
These results indicate that the larger size of the PGs in HT-29 cells, compared to the FEMX cells, is due to more GAG chains attached to each core protein, or larger core proteins.
Cost considerations have led to most oligonucleotides being synthesized at dedicated off-site facilities or large core facilities.
Our data also strongly favour the concept that quantitative perfusion CT can better identify treatment responders compared to standard clinical/non-contrast CT selection and also those who have little to gain (i.e. no mismatch, or large core).
This low spontaneous intracranial haemorrhage rate compared with the 13.2% rate of spontaneous intracranial haemorrhage (15/113) seen in the combined group of treated patients with either large cores or without target mismatch on quantitative 'off-line' perfusion CT analysis (P < 0.001).
In contrast, total internal reflection fluorescent microscopy (TIRF-Microscopy) enables selective visualization of synaptic vesicles or large dense core vesicles (LDCVs) at the membrane close to the glass/cell interface, i.e. at the footprint of the cell [4] [12].
Perfusion CT more reliably identifies the extent of irreversibly damaged tissue (ischaemic core) than non-contrast CT (Murphy et al., 2006; Muir et al., 2007; Wintermark et al., 2013), and demonstrates that reperfusion therapy may be futile or even potentially harmful (Campbell et al., 2010) when the ischaemic core is large, or the perfusion lesion is particularly severe (Yassi et al., 2013).
The AT chromosome consists of a central part or core and large TIRs that occupy 14.3% of the genome.
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