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Micro-CT-based finite element models having uniform hard tissue material properties were created from 54 cores of human trabecular bone taken from four anatomic sites (age = 70 ± 11; 24 male, 27 female donors), which were subsequently biomechanically tested to failure.
Finally, tissue micro arrays containing cores of human OS tissue were stained using immunohistochemistry and EPHA2 staining was correlated to clinical outcome measures.
We detected a strong signal for PDGFRα in approximately 70% of tissue cores of human prostate and all the samples from skeletal metastases by immunohistochemistry [13].
To assess the clinical relevance of EPHA2 expression in OS and to investigate if EPHA2 could be considered a biomarker for OS, TMAs containing 647 cores of human primary OS samples were stained and analysed for EPHA2 expression.
Two TMAs containing a total of 647 cores of human primary OS samples (corresponding to 130 OS patients) and 20 control tissue cores, were stained and analysed for EPHA2 expression (Supplementary Figure S1A) and then correlated to clinical and survival data.
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The concept of nature exists in the core of human geography, and the relationship between humanity and nature is one of the most important research themes.
Dignity and respect are at the core of human rights.
"The core of human ecology is real simple," says David F. Hales, president of the college.
Success would, those scientists believed, reach to the very core of human intellectual endeavour.
But where Mr. Lucas and Mr. Spielberg drift into cartoonishness, Ozep and Barnet preserve a core of human reality.
Perhaps it supplied a way of trying to find that core of human personality which seems so elusive when moving from culture to culture.
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