The resulting organizational models exhibited strong similarities to that presented in Fig. 4Aiii, in particular with respect to the complex core (defined as the proteins with more than one attached partner).
The strict core, defined as present in all 21 genomes, revealed 893 gene families of which 643 only had single homologs per genome.
The concept of a genomic core, defined as the set of genes ubiquitous in all genomes of a monophyletic group, has become crucial in comparative and evolutionary genomics.
Essentially, after the gene clustering procedure, two sub-sets of gene clusters were identified, a modified core, defined as a gene cluster that had only one member from every strain, and a modified distributed set, defined as a cluster which had fewer than all strains as a member, but greater than just a single strain.
Necrotic cores were defined as areas free of extracellular matrix between the luminal fibrous cap and the collagen-rich outer intima and/or remaining media [ 28, 39].
The core diameter (defined as the shortest distance inside the core) is 94 µm, and the angle of the full acceptance cone is 60 mrad (NA of 0.03).
A core genome alignment was created from the consensus sequences, with the core genome defined as nucleotide sites shared by all sequences (alignment columns that did not contain a gap character or unknown nucleotide identity).
The clusters were determined by MCL clustering, as described in the methods section, and are referred to as Homolog Gene Clusters (HGCs), The "soft core" is defined as all HGCs found in at least 95% of all genomes and the "strict core" is defined as all HGCs found in at least 100% of all genomes.
The number of so-called core golfers, defined as people 18 years old and up who play eight or more rounds a year, has declined even more precipitously.
OBSERVATIONS of elliptical galaxies show a positive correlation1,2 between total luminosity and core radius, defined as the radius at which surface luminosity becomes half of the central value.
