Sentence examples for core trial from inspiring English sources

Mason, W. P. End of the road: confounding results of the CORE trial terminate the arduous journey of cilengitide for glioblastoma.

We decided to begin work on the first stage, beginning with the pre-trial documents and other heterogeneous IMT-related documents that were stored (in no particular order) in two boxes, before moving on to the core trial documents (arguments, briefs, and evidence in document books).

The Continuing Outcomes Relevant to Evista (CORE) trial, designed to determine the effect of raloxifene on the incidence of invasive breast cancer, was a 4-year follow-up study to the 4-year Multiple Outcomes of Raloxifene Evaluation (MORE) osteoporosis treatment trial.

The CORE trial will take almost 4 years to complete.

In the core trial, the starting dose for both insulins was 10 Units.

313 Auditing involves periodic independent review of core trial processes and documents.

*IM101043, without infliximab arm; **Number represents total number of abatacept exposed patients exposed during both double-blind and open-label; five core trials N = 2,689, overall N = 4,134.

During the 8 years of the MORE and CORE trials, the overall incidence of breast cancer, regardless of invasiveness, was reduced by 58% in the raloxifene group compared with the placebo group (HR = 0.42, 95% CI = 0.29 0.60; P < 0.001).

Similar to data across the three core trials, only two individual SAEs were seen in >1% of patients overall, and these were epilepsy-related: convulsion (n = 36, 3.0%) and status epilepticus (n = 13, 1.1%).

The effect of raloxifene on the incidence of cardiovascular adverse events in postmenopausal women has been reported in the MORE and CORE trials (Dayspring et al 2006; Ensrud et al 2006).

During the 8 years of the MORE and CORE trials, the incidence rate for venous thromboembolic events was 2.2 and 1.3 events per 1000 woman-years for the raloxifene and placebo groups, respectively.