Current guidelines recommend a 12-core systematic biopsy following the finding of an elevated serum prostate-specific antigen (PSA).
MR-guided biopsies can be particularly useful in indicating to the physician the importance in sampling these regions, as one study reported that anteriorly located cancerous lesions were missed in up to 46% of 12-core systematic biopsies [ 44].
The Drammen Project has as its core a systematic treatment program directed at patients who have not profited adequately from previous treatment attempts.
Despite its rapidity, this review adheres to the core principles of systematic reviews in order to avoid bias and ensure rigor.
Using 6-substituted purine and deaza purines as the core scaffolds, a systematic and structure guided series of modifications provided low nM inhibitors with broad-spectrum antimicrobial activity.
A systematic core design method is developed to design Gd-bearing fuel assembly having two types of Gd rods, low-wt%-Gd rod and high-wt%-Gd rod.
One indisputably common element between the two schools is the preoccupation with the problem of validity, or Geltung, which is arguably the systematic core of Neo-Kantianism in general (Krijnen 2001, 84).
Following a meeting to agree upon the core agenda, a systematic literature review was undertaken to identify all relevant data.
We first provide some background, briefly outlining the rationale and core procedures of systematic reviewing, then providing an overview of the value and methods of conversation analytic and related discursive research.
