Sentence examples for core structural elements of from inspiring English sources
The structural alignments generated by these searches showed that the transcobalamin C-terminal domain aligns completely with all core structural elements of the β-GF, including a β-sheet of 5 strands and a helix between strands 2 and 3.
These simulations were conformationally stable, with an overall Cα rmsd of ∼4.5 Å over 20 ns for each Kir channel and of ∼3 Å for the core structural elements (i.e., excluding the loops).
The fingerprint concept is based on the fact that sequences of proteins from a family hold in common subsequences (sequence motifs) that usually relate to key functional elements or core structural elements; the motif is any conserved element seen in the alignment of sequences forming a family.
Structural comparison of actin, Arp2 and Arp3 shows that actin is a very compact molecule whereas Arp2 and, especially, Arp3 possess various extended loops between the core structural elements ([ 118] and Figure 2).
To increase the avidity of LyP-1 constructs to p32, we synthesized a dendritic form of LyP-1 on solid phase using lysine as the core structural element.
The BLAST alignment positions one long gap in the Ago2 sequence (between the ISR and the DAG, slanted lines mark BLAST residue matches) that omits a core secondary structural element of eIF4E, while gaps in the reported alignment interrupt secondary structure elements.
Most T6SS core components correspond to structural elements of the secretion machinery.
Despite the low sequence identity between this domain and the Ubq (below 20%), the hydrophobic core and key secondary structural elements of the Ubq fold are conserved [ 54].
Each family displays similar hydrophobicity patterns (yellow highlights) corresponding to the secondary structural elements of the core fold.
Several structural elements of RNAP core also come in close proximity with promoter spacer located between the −10 and −35 promoter elements (Murakami et al, 2002).
The good topoisomerase I inhibitory activity of 1 and the lack of SAR prompted us to design and synthesize a series of fluoroquinophenoxazine analogs to systematically evaluate the SAR and to probe the structural elements of the fluoroquinophenoxazine core toward topoisomerase I enzyme target recognition.
