Sentence examples for core structural elements from inspiring English sources

The central finding described here is that some of the Crenarchaeota and Korarchaeota possess actin-like proteins that are not only monophyletic with the eukaryotic actin family but also are structurally similar to Arp2/3 in that they contain multiple, extended inserts between core structural elements that are missing in eukaryotic actins.

A novel series of quinoxaline derivatives, as Multi-Target-Directed Ligands (MTDLs) for AD treatment, were designed by lending the core structural elements required for H3R antagonists and hybridizing BACE 1 inhibitor 1 with AChE inhibitor BYYT-25.

Apparently, the spacers between the domain core structural elements were minimal in size, just enough to span the spatial gaps, connecting the structure.

These simulations were conformationally stable, with an overall Cα rmsd of ∼4.5 Å over 20 ns for each Kir channel and of ∼3 Å for the core structural elements (i.e., excluding the loops).

Structural comparison of actin, Arp2 and Arp3 shows that actin is a very compact molecule whereas Arp2 and, especially, Arp3 possess various extended loops between the core structural elements ([ 118] and Figure 2).

The structural alignments generated by these searches showed that the transcobalamin C-terminal domain aligns completely with all core structural elements of the β-GF, including a β-sheet of 5 strands and a helix between strands 2 and 3.

To increase the avidity of LyP-1 constructs to p32, we synthesized a dendritic form of LyP-1 on solid phase using lysine as the core structural element.

A comparison showed that the core structural element in EndoU, Colicin E5, colicin D and RelE is a similar strand-β-sheet unit.

We present several alternative approaches to identify and build the key hotspot interactions within both core secondary structural elements and variable loop regions and evaluate the method's performance in natural-interface recapitulation.

Such omissions and interruptions of core secondary structural elements cast doubt on the validity of the alignments between the Ago2 MC sequence region and the eIF4E motif.

The overall fold of the CopB N-domain is very similar to its homologues in that it shares core secondary structural elements despite low sequence identity [ 17, 20, 38, 39].