Our results indicate that regardless of the presence or absence of shared taxa, a core set of metabolic functions defines the non-diseased and diseased respiratory tract DNA viromes.
Intriguingly, despite the considerable variability in the composition of the gut microbiota, metagenomic shotgun sequencing demonstrates that these diverse communities share a core set of gene functions in the microbiome.
Here, we describe an approach that uses phylogenetic profiling to identify a core set of ciliary function proteins.
In each of these case studies, it can be observed that a core set of genes and functions – typically related to replication and encapsidation – are conserved whereas auxiliary functions, possibly of contextual adaptive value, can be gained and lost in time as viruses co-evolve with their preferred hosts.
Comparisons of the B. vafer genome with the previously published B. floridanus and B. pennsylvanicus genomes clarified the core set of genes and functions shared by this mutualist group.
First, each domain contains a core set of regulatory elements that function in a hierarchical manner.
These results strongly suggest that similar reductive pressures have led to convergence upon a core set of eukaryotic cellular machineries functioning in the remnant cytoplasmic compartments surrounding the plastids in the two lineages (i.e., their "periplastidial" compartments).
Collectively, the canonical and noncanonical pathways converge on a core set of transcription factors that function to initiate and maintain EMT: SNAIL (SNAI) 1/2, zinc finger E-box binding (ZEB) 1/2, Twist 1/2, Goosecoid and others [ 8].
Through comparing data generated in the current as well as our previous pharmacological study, we identified a core set of 115 genes - whose functions are associated with fatty acid and metabolic and organic acid biosynthetic processes - that contribute to line level differences in stress coping styles.
The intersection of all four genotypes reveals 4,097 ORFs that represent the core set of orthologs with the same function or activity in all four genomes.
