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This unique situation provides a detailed reconstruction of the local vegetation development and fire history for the area surrounding the megalithic graves, by investigating a peat core sequence, and backed by 11 AMS 14C measurements and archaeological data.
Trans-cleavage activity of the circular HDV-like ribozyme was comparable to linear permutations of HDV ribozymes containing the same core sequence, and was shown not to be due to linear contaminants in the circular ribozyme preparation.
Putative sites reported here have 100% conservation of the core sequence and 75% conservation of the matrix sequence.
We introduced different sized oligo loops between the DNAzyme core sequence and the ASON sequence (Figure 1).
Medaka and stickleback have one PENK gene and this lacks the third core sequence and has a degenerate sixth core sequence.
Additionally, the active transcriptional structure formed between HS2 core sequence and ε-globin gene promoter was affected in K562-SATB1-RNAi K562-SATB1-RNAi K562-SATB1-RNAien HS2cellsand γ-globin gene promothe associationtely decreased (Fig. 4F).
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We would like to acknowledge the support of the Wellcome Trust Sanger Institute core sequencing and informatics groups.
The gene located on zebrafish chromosome 7 (PENKa) has an insertion between the two first core sequences and is missing the third core sequence, while the gene on chromosome 2 (PENKb) does not have this insertion and has retained the third core sequence, but has a degenerate sixth core sequence, as described earlier [25], [26].
Since HCV core protein is thought to play a major role in HCV pathogenesis, it would be worthy to determine whether negative result in anti-core antibody assay (and/or increased levels of anti-core+1/ARFP) could identify patients harbouring mutated core sequences, and whether this unusual serological pattern is associated with a particular pathology during HCV infection.
The authors thank the Wellcome Trust Sanger Institute core sequencing and informatics teams.
We thank the core sequencing and bioinformatic teams at the Wellcome Trust Sanger Institute for their support.
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CEO of Professional Science Editing for Scientists @ prosciediting.com