Sentence examples for core reprogramming from inspiring English sources

This can be achieved by inducing the expression of three core reprogramming factors Oct4, Sox2, and Nanog.

Some studies on the deep relationships between core reprogramming factors and CSC phenotype or carcinogenesis have been reported.

Fong et al. propose that DKC1 binds to XPC, which in turn binds to two of the core reprogramming factors.

Now, Fong et al., including several of the researchers involved in the 2011 work, have identified another unexpected partner for the same two core reprogramming factors.

Fong et al. found that when embryonic stems cells from mice are depleted of the DKC1 complex, the activation of important pluripotency-related genes by two of the core reprogramming factors is markedly reduced.

In 2011, researchers discovered that a protein complex called XPC which is normally involved in DNA repair also helps two core reprogramming factors to activate an important gene related to pluripotency.

A core group of reprogramming factors are known to activate networks of genes that are normally only expressed in stem cells, and by doing so trigger and maintain a pluripotent state.

This setting with nucleosome depletion may allow the core pluripotency factors to bind to their target genes relatively easily and construct the core pluripotency networks during reprogramming.

The programmable logic blocks and routing resources of an FPGA core can be reprogrammed to test the other embedded cores within SOCs such as RAM and DSP cores.

However, our model suggests that under certain circumstances, amplification of low-level fluctuations in transcriptional status (transcriptional "noise") may be sufficient to trigger reactivation of the core pluripotency switch and reprogramming to a pluripotent state.

Asf1a is also essential for acetylation of newly synthesised H3 at lysine 56 (H3K56ac) (Burgess & Zhang, 2013; Gonzalez-Munoz et al, 2014), and it has been suggested that Asf1a regulates the expression of core pluripotency genes during reprogramming by increasing global H3K56 acetylation levels (Gonzalez-Munoz et al, 2014).