Sentence examples for core regulators from inspiring English sources
Our results show that except for regulated by the core regulators, HOX family of genes could form their own internal and autoregulatory loop to control the developmental processes of human ES cells.
Because most lignocellulase genes that are down-regulated in the presence of acute ER stress belong to the CLR-2 or XLR-1 regulons, it seems likely that RESS results to a great extent from the down-regulation of these core regulators.
These transcripts included cell cycle core regulators (cdc2, CYCK1 and CYCB), cell cycle entry/exit-regulated proteins (APC components), cullin, prohibitin, anti-silencing function 1 (ASFtsZ FtsJ, FtsJ, MinD, GlsA and Hsp70.
For example in the case of the Galactose network of E. coli, there are in fact two core regulators that bind the small molecule D-galactose, and which each regulates transporters and enzymes [4], [5].
In this study, we characterized the core regulators of c-di-GMP turnover in B. amyloliquefaciens PG12.
Moreover, the concept of interplay between sequentially deployed core regulators is likely to represent a design principle widely applicable to the transcriptional control of mammalian development.
ATG7 has also been documented as a core regulator in caspase-8 inhibition-induced autophagic cell death in mouse L929 skin fibroblast cells (Yu et al., 2004).
The myosin phosphatase is also a well known core regulator of the actomyosin pathway, inhibiting the myosin activity [18].
Those results clearly show that miR-200a is a core regulator of module 25, most probably with other members of the miR-200 family.
It has also been shown that hES cells and mouse spermatogonial cells express the core regulator of promiscuous expression of tissue specific genes in medullary thymic epithelial cells, the Aire gene [8], [15].
Moreover, Nishikawa et al. and our group have shown that the core regulator Aire, which promotes the promiscuous expression of tissue-specific genes in the thymus, is expressed in ES cells and induced pluripotent stem cell iPS) cells [11], [12].
