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Together, these results lead to a "residue-nucleotide" interaction map upon which to base AAA+ core regulation.
While various amendments have been made to the bill over the years, the core regulation has survived: in 2017, it's still illegal for more than three people to dance in an any unlicensed NYC space.
In response to the concentration variation in HIF, the transcriptional cascade HRE becomes active, but is not directly involved in the core regulation of hypoxia or normoxia pathways.
The top 10% most connected genes in this module are from four different tissues and might constitute core regulation pathways involved in communication between tissues.
We found that 237 TFs and 140 high-confidence TcoFs may be involved in the core regulation (1000nt upstream) of the 162 OC-associated miRNAs.
A core regulation is defined as a regulation network which is identical within a subgroup of samples and represents at least T% of the total number of samples (step 4 Figure 1).
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So there are some core regulations that we've got to maintain.
The 110 core regulations consisted of 28 distinct subnetworks.
DERA identified 110 core regulations consisting of 28 disconnected subnetworks for TNBC.
There were 119 differentially expressed genes in TNBC that contributed to the core regulations.
DERA identified 256 core regulations that occurred in at least half of the TNBC samples in the discovery data (TCGA_Array).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com