Sentence examples for core pathological features from inspiring English sources

This study demonstrates that alterations in the trajectory of neuronal growth throughout the lifespan are a core pathological features of idiopathic and syndromic autism.

The BDNF pathway has been consistently linked to core pathological features of amyloidosis and tauopathies because this trophic factor is able to regulate the production and the neurotoxic effects of amyloid b42 and Tau protein hyperphosphorylation [ 43, 44].

Detection of neuronal soma volume deficit in dup(15) autism with significantly smaller brains may strengthen the hypothesis that reduced volume of neuronal soma is a core pathological feature of idiopathic and syndromic autism.

Next, we analyzed the association between FAS expression in the biopsy cores and pathological features of RP specimens.

However, physicians need an accurate grading determination in two different settings: (1) In patients whose first-line treatment is surgery, the identification of aggressive pathological features from the core biopsy can select patients who will require adjuvant chemotherapy.

Cores, as a pathological feature, can be associated with defects in several genes but these disorders are not central core disease.

We have categorized the genes of the core network with regard to the four pathological features described by Hwang et al. No genes from the pathological feature category synaptic degeneration were found in the core network, but it should be noted that only one of the 333 DEGs in the original mouse study was a member of this category.

Immunohistochemistry showed that HEXIM1 was ubiquitously expressed with widespread intranuclear high intensity in most cores and therefore non-discriminatory for any pathological features and is not discussed further.

We mapped these pathological features on the nodes in our core network and examined how the genes in our network may relate to disease progression.

Although the causes of PD have not been identified in the majority of cases, patients share the core clinical symptoms of bradykinesia, akinesia and rigidity, and the pathological features of dopaminergic neuronal loss and the presence of Lewy bodies.

We aim to review the radiological and pathological features of FEA and evaluate the significance of FEA on needle core biopsy.