Here, we report on the contribution of Drosophila CenH3CID to recruitment of BubR1, a conserved kinetochore protein that is a core component of the spindle attachment checkpoint (SAC).
Here, we report on the contribution of the N-terminal domain of Drosophila CenH3CID (NCenH3CID) to recruitment of BubR1, an evolutionarily conserved kinetochore protein that is a core component of the spindle attachment checkpoint (SAC) [13], [14], [15].
Results described above indicate that, in Drosophila, NCenH3CID is involved in recruitment of BubR1, an evolutionarily conserved kinetochore protein, which is a core component of the spindle attachment checkpoint (SAC).
MAD1 encodes a core component of the spindle assembly checkpoint (SAC), and we compared the obtained CIN rate with those reported previously for WT and mad1 Δ by using ALF (Li and Murray 1991) and CTF assays (Spencer et al. 1990).
Centrioles are cylindrical structures found at the core of the mitotic spindle pole, which also act as basal bodies to nucleate the formation of cilia.
The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
(f) Maximum spindle speed (min−1)—Rotations of the spindle of a CNC turning centre per minute is its spindle speed.
Most investigations on dynamic characteristics of the spindle system were confined to ball-bearing-type spindles.
We are currently studying spindle assembly, spindle positioning, chromosome segregation, the evolution of the spindle, and the possible connection between errors in mitochondrial function and errors in spindle function.
To evaluate the performance of the spindle, many techniques have been proposed to measure the spindle error motion.
