Sentence examples for core of the plaque from inspiring English sources
Subsequent to cap thinning a disruption or tear in the cap causes blood to enter the lipid core of the plaque determining an initial phase of intraplaque haemorrhage.
ATP6V1B2, SNAP25, and VAMP2 (N – P ) all show a halo of elevated protein concentration in the region surrounding the dense core of the plaque.
In conclusion, the presence of astrocytes and microglia around the amyloid core of the plaque is seen both in the human and in the Tg mice.
The tau pathology is mainly intracellular: accumulation of tau may occur in the cell body (neurofibrillary tangle = NFT), in the dystrophic axons surrounding the amyloid core of the plaque, and in the neuropil threads, which are mainly dendrites.
8, 10 These plaques are prone to erosion or rupture, exposing the core of the plaque to circulating coagulation proteins, causing thrombosis, sudden occlusion of the artery lumen, 8, 10 and usually an acute coronary syndrome.
The TG2 antibody strongly stained intact endothelium in brachiocephalic arteries from apoE deficient mice TG2 but also detected small clusters of cells within the shoulder regions of mouse plaques and within the core of the plaque (Fig. 1).
The core of the plaques is an amyloid beta (A β) protein.
Plaque Lp-PLA2 co-localized with C. pneumoniae, macrophages and CD4+ lymphocytes by IHC in the shoulder and necrotic core of the plaques as has been noted by others [9].
By tissue protein overlay, the AQP1-Xpress probe did not decorate the entire surface of Aβ-immunoreactive plaques, but the core of the plaques often expressed a nodular or irregular-shaped AQP1-Xpress-immunoreactivity (Fig. 7b, panel a).
The amyloid plaques (arrow) are positive for VAMP2 and SNAP25, whereas synaptophysin does not stain the core of the plaques and punctate lobular profiles decorating the plaque are positive for synaptophysin.
Our study highlights that this switch of plaque quality by lithium could be mediated by astrocyte activation and the release of heat shock proteins, which concentrate in the core of the plaques.
