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To evaluate the sensitivity of our core model parameters and identify critical enablers of resilience, we varied parameters and model assumptions within a range thought to bound realism: relaxed compliance (60%); delayed strategy implementation thresholds (day after 30 or 100 individuals are diagnosed within the community); relaxed rescinding of strategies (3 cases in 7 days).
Note that the set of core model parameters has the same values as described in Sect.
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An analytical lumped-parameter core model has been developed to treat the coupling between neutronics and thermal-hydraulics.
It replaces the exponent in shrinking core model by a new parameter n. r = frac{{{text{d}}x}}{{{text{d}}t}} = {{k}}(1 - x)^{n} (8 where k is the reaction rate constant, and n is the reaction order.
First, 30 core samples were used to calibrate the model parameters, but the same core samples were reused for the model validation.
Table S1: Kinetic parameters of the core model.
The parameters of the core model are taken from the Kearns model, for which they were partly determined experimentally and partly taken from the literature.
Taken together, we verified our findings with an additional NF-κB model, which differs in structure and parameters from the core model.
We next use the derived core model to study the most sensitive parameters with respect to the stimulated steady state of active NF-κB.
The reactor core model is developed through a lumped parameter thermo-neutronic coupled layout of the plant.
Here, we determine the transition between modes of dynamical behaviour, in particular, from stable steady states to sustained oscillations (stable limit cycle oscillations) for each parameter of the core model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com