Sentence examples for core feedback loop from inspiring English sources

Digital leaders no longer manage; rather, they enable workers to innovate and facilitate the core feedback loop of user responses to firm decisions and execution.

But of course, in games, the hero never makes it, the girl can never help him escape violence, because in games, violence is often the core feedback loop, the defining mechanism.

In the core feedback loop of the Drosophila clock, transcription factors CLOCK (CLK) and CYCLE (CYC) heterodimerize and activate transcription of period (per) and timeless (tim) through binding to their upstream and intronic E-boxes.

The PER and CRY proteins also heterodimerize and inhibit CLOCK/BMAL1 activity leading to reduction in PER and CRY expression, thereby completing the core feedback loop responsible for the circadian rhythm.

Exciting studies also suggest that Timeless could play a role in conveying phase-resetting zeitgebers arising from DNA damage to the core feedback loop.

Among alternatively spliced genes of the central circadian oscillator, CCA1 and LHY represent the core feedback loop whereas PRR7 and PRR9 play roles in the morning loop [ 4].

Two core feedback loops have been described in the mammal; they consist of two period (mPer) genes and two cryptochrome (mCry) genes (negative loop), and basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) domain proteins BMAL1 (MOP3) and CLOCK (positive loop) [7, 8].

We use the pitcher-plant mosquito, Wyeomyia smithii (subfamily Culicini, tribe Sabethini), to test whether evolutionary divergence of the circadian clock genes in this species, relative to other insects, has involved primarily genes in the core feedback loops or the post-translational modifiers.

Relative divergence does not differ between core feedback-loop genes and post-translational modifiers of those genes in a Sabethine species (W. smithii) that has experienced a continual northward dispersal into temperate regions of progressively longer summer day lengths as compared with six other insect taxa.

After aligning translated W. smithii contigs and singletons from this transcriptome with other insects, we determined that there was no significant difference in the average divergence of W. smithii from the six other taxa between the core feedback-loop genes and post-translational modifiers.

Cryptochrome, which functions as part of the core clock feedback loop in mammals, serves as a photopigment in the fruit fly [15].