Caspases, the core enzymes responsible for executing apoptotic cell death, are synthesized as inactive zymogens and divided into initiator (caspase-2, -8, -9, and –10) and effector or executioner (caspase-3, -6, and –7) caspases.
Despite being the core enzymes responsible for the apoptotic phenotype, caspase activation is a downstream level of apoptosis (in the execution phase).
Among these, xylanases (β-1,4-Endoxylanases, EC 3.2.1.8) are the core enzymes responsible for the degradation of xylan into monomers through the random cleavage of β-1,4-glycosidic bonds in the xylan backbone [ 4, 5].
Of the four core enzymes responsible for mtDNA replication, the replicative helicase Twinkle and DNA polymerase γA (POLGA) are similar to homologues in Drosophila, DNA polymerase γB (POLGB) is quite divergent and mitochondrial-specific single-stranded binding protein (mtSSB) is apparently absent.
Fructose bisphosphate aldolase (FBA, or aldolase) is a core carbon metabolic enzyme responsible for the aldol cleavage of fructose-bisphosphate into glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP) sugars in glycolytic reactions, and the reverse aldol condensation of these triose sugars to fructose-bisphosphate in Calvin cycle and gluconeogenic reactions.
Garner et al. showed that lack of HS primary central core, after deletion of Ext1, the enzyme responsible for building up the central core of 1,4-linked uronic acid (D-glucuronic acid or L-iduronic acid) and D-glucosamine, results in highly defective mammary development [ 20].
The proposed ancient character of the T. brucei import system prompted us to re-evaluate features of N-MTSs in this flagellate, the enzyme responsible for their processing and the character of the core proteins.
They also measured the activity of telomerase, which is the enzyme responsible for repairing telomeres.
Potentiation seems to take place when one compound destroys the liver enzyme responsible for detoxicating the other.
It does this by "switching off" the enzyme responsible for the browning (called polyphenol oxidase) using pressure fluctuations generated by steam.
