Sentence examples for core effectors of from inspiring English sources

The CASPs are believed to be the core effectors of apoptosis.

It is notable that only the RxL part of the RxLR seems to be highly conserved within potential core effectors of Phytophthora and downy mildews, similar to the situation in Plasmodium [ 90], in which the same residues seem to play a vital role for delivering its effectors to the host cytoplasm [ 90– 92].

This miRNA-loaded Ago is termed the RNA-induced silencing complex (RISC), and is the core effector of RNA interference (RNAi) [1].

However, there might be some core effectors that are the hallmark of an entire group of pathogens and which are crucial for pathogenicity (Sharma et al. 2014).

A group of 21 core effectors, including all those encoded within LEE and a number of non-LEE effectors, are shared by all A/E pathogens [ 79, 80].

Orthology analyses revealed the conservation of 28 RxLR-like core effectors among Phytophthora species.

Our reconstruction of the molecular interactions affected by glaucoma revealed multi-domain biological networks controlling activation of ONHAs at the level of intercellular stimuli, intracellular signaling and core effectors.

Comparing the draft genome sequences of the three xanthomonads with that of Xcv allowed us to identify the core effectors conserved in all four strains as well as strain-specific effectors (Tables 2, 3, and 4).

TAZ and YAP (yes-associated protein), two mammalian homologous to Drosophila Yorkie, serve as two core downstream effectors of the Hippo signaling pathway which comprises an upstream kinase cascade and a downstream transcription module (Fig. 1).

We note that while the core effector-binding region of CED-10 is 100% conserved with human Rac1, Rac2 and Rac3 (YIPTVFDNY), RAC-2 has nonconservative variants in two residues (YI LTVFD TY), and mutation of many of these residues in human Rac1 disrupt binding of Pak and other effectors (Westwick et al. 1997).

Comparisons of these have led to the identification of core effector gene sets and to explain some of the differences in host-specificity between pathovars.