We're looking at core components of biology and why they may have formed the specific way they have and how that can be controlled by chemistry.
Both hDlg1 and hScrib are core components of polarity control at adherens junctions, and MAGI-1 is essential for tight junction integrity.
A subset analysis of patients who failed to achieve at least an ACR20 response at Week 12 (n = 321/772, 41.6%) demonstrated reductions in ACR core component values at Week 12 (Table 3).
A summary of the improvement in the ACR core components and morning joint stiffness at week 24 in patients re-randomised at week 12 is provided in online supplementary table S1.
At institution level, core components of the NHHI are alcohol-based handrub at the point-of-care, healthcare worker education, and HH auditing with performance feedback using the WHO '5 Moments' methodology.
Studies in mammals have suggested alternative branches of the NMD pathway, which differ in the dependence on the cofactors UPF2, EJC core components and UPF3B, but converge at the point of UPF1 phosphorylation (Gehring et al, 2005).
Five of 16 CRGs replied that the Cochrane Handbook should serve as a general standard guideline for reporting in the review, although no detailed instructions or any recommendations for reporting the details or at least core components of complex interventions such as acupuncture were provided to authors.
The ultra-high resolution of TEM offers the intriguing possibility of detecting core components of the DNA repair machinery at the single-molecule level and visualizing their molecular interactions with specific histone modifications.
On my agenda, beyond promoting the research, curriculum development, the maintenance and growth of the collections, and the education and outreach missions of the Museum, will be fund-raising so that these core components of the Museum can operate at the highest level in the years to come.
