Sentence examples for core coding region from inspiring English sources

A 21-nucleotide siRNA, which can hybridize to the HCV core coding region with a single G-U base pair, suppressed weakly transgene expression in mice.

An internal ribosomal entry site (IRES), containing the 5′UTR and part of the core coding region, forms a stem-loop structure and supports translation initiation of HCV genome in a cap-independent manner [21, 22].

Thus, pUC1.2xHBV/NL lacked 562 nt of HBV DNA from the 3′‐terminal half of the core coding region to the 5′‐coding region of the polymerase coding region, resulting in non‐functional preCore/Core and polymerase proteins.

In contrast, non-coding core chromosomal regions had an average log2 ratio of -1, indicating low nucleosomal occupancy, and were less variable than core coding regions.

Significant differences between rates of synonymous (dS) and nonsynonymous (dN) substitutions in the variable and core coding regions of Bm genomes were detected.

Differences between rates of synonymous (dS) and nonsynonymous (dN) substitutions in the variable and core coding regions were analyzed with the Wilcoxon rank sum test.

Using a liver cell model containing functional genomic-length HCV-1b RNA we tested whether 2′-O-methyl-modified Dz, designed to recognize a highly-conserved RNA sequence located within the core-E1 coding region, could recognize and cleave its target sequence in the structural context of a functional HCV RNA molecule.

This unusual serological profile could be linked to several synonymous mutations in the core and core+1/ARFP coding region that result in major changes in predicted RNA structure, and that may favour core+1/ARFP production.

We show that HCV patients who do not produce normal anti-core antibodies have unusually high levels of antit-core+1/ARFP and harbour several identical synonymous mutations in the core and core+1/ARFP coding region that result in major changes in predicted RNA structure.

This places the enhancer region 5' to the Drosophila synthetic core promoter and GAL4 coding region.

Only few HVS defining mutations for L0d2c exist (only 294a distinguishes the L0d2c from the L0d1,2 core haplotype), while several coding region mutations separate L0d2c from L0d2ab [ 12], which explains the differences in divergence times.