Sentence examples for core cellular processes such from inspiring English sources
This second largest group of current drug targets functions as ligand-activated transcription factors and regulate core cellular processes such as cell growth and differentiation, inflammatory responses and metabolism.
Despite the rapidly expanding interest in DUBs as likely critical regulators of core cellular processes such as protein trafficking [47], [48], the physiological roles and targets of most of the known or predicted deubiquitinating enzymes remain unknown.
In both the starvation control and the methanol switch experiment, expression of genes predicted to be involved in many core cellular processes such as cell structure synthesis, ribosome synthesis and protein production, flagellar synthesis, and iron uptake were down-regulated, conserving energy.
Their functional versatility also extends to other core cellular processes, such as maintenance of cell shape (McNiven et al., 2000) or centrosome cohesion (Thompson et al., 2004).
AS plays a pivotal role in controlling core cellular processes, such as proliferation, metabolism, and apoptosis, and fundamental physiological decisions, such as maintenance of pluripotent state or induction of a specific differentiation lineage [ 18].
These modifications occur primarily within the histone amino-terminal tails protruding from the surface of the nucleosome as well as on the globular core region and regulate key cellular processes such as transcription, replication, and repair (Kouzarides 2007).
A large fraction of the core genes was assigned to categories with general cellular processes such as energy production and conversion, amino acid transport and metabolism, translation, and transcription.
Surface residues and hotspot residues at the interface of PPIs form the core regions, which play a key role in modulating cellular processes such as signal transduction and are used as starting points for drug design.
Key core cellular processes include exocytosis, endocytosis, actin and microtubule cytoskeletons, and small GTPases such as Rho and Cdc42 (see [ 44] for a review).
The consistently high expression levels for core eukaryotic genes are not, in themselves, particularly surprising: this category includes genes involved in basic cellular processes such as DNA replication and repair, mitochondrial iron-sulphur cluster assembly, intracellular trafficking and in some metabolic pathways such as glycolysis and the pentose phosphate pathway.
