Sentence examples for core cellular function from inspiring English sources
The regulation of 11 sulfatases during stressful conditions suggests that these genes are heavily involved in the core cellular function of R. baltica.
It is conceivable, then, that SET2 subtype genes have been conserved for RNase polymerase II-interaction as a core cellular function and, thus, unlinked with multicellularity.
This idea may explain why CHR2 carries features typical for plasmid-type partitioning, as well as its unique core cellular functions.
Nonetheless, it is interesting to note that this group was also significantly depleted in transcripts encoding proteins involved in core cellular functions such as translation functions.
HSF1 also orchestrates a broad network of core cellular functions associated with proliferation, survival, protein synthesis and glucose metabolism, thus enhancing oncogenic transformation [ 8, 9].
These cases suggest that some genes involved in core cellular functions were retained to increase dose, and have been constrained by strong purifying selection.
Moreover, stress responses preserve core cellular functions at the expense of 'accessory' ones [ 63– 65] and therefore must be tightly regulated over time [ 11].
Loss of group 1 genes results in pleiotropic effects (i.e., multiple sensitivities), likely because these genes are involved in core cellular functions.
However, there is an opportunity to exploit synthetic lethalities specific to particular populations of cancer cells created by the homozygous loss of genes responsible for core cellular functions.
