Exact(2)
The council has said it wants to have a "core branch network" of libraries.
Four individuals had a deletion of exon 7 and four individuals carried a 1-bp deletion in exon 9. Details of the genetic analysis of the core branch of Family LA have been described elsewhere (Klein et al., 2000).
Similar(58)
These nanostructures provide three regions for modification with bioactive agents, namely, the core, branching zone, and branch surface [13].
We've seen in our lifetimes a rapid evolution in the wearables family — it has brought together four core branches of technology into a new class of device.
PAMAM Dendrimers are synthetic spherical macromolecules with a well-defined surface, comprising a core, branching sites and a large number of terminal groups [12].
The incorporation of photoresponsive moieties at various components of dendrimer such as core, branches or at the peripheral end exaggerates its significance in various allied fields of nanotechnology which includes sensors, photoswitch, electronic widgets and in drug delivery systems.
Altogether our data demonstrate that not LAM capping, but mannan core branching of LM/LAM plays an important role in mycobacterial pathogenesis in the context of innate immunity.
Collectively, our data indicate that the M. marinum mptC mutant is defective in both mannose cap extension of LAM as well as mannan core branching of LM and LAM.
The level of mannan core branching is one of the structural features that determines TLR-2 activity (Nigou et al., 2008).
It is intriguing though that in the M. marinum zebrafish infection model an effect of LM and/or LAM mannan core branching on virulence can be shown.
This demonstrates that not LAM capping but mannan core branching of LM and/or LAM is a virulence determining factor in the context of innate immunity.
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