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Due to the expensive nature of core analysis, the "log-only" option of determining water saturation has been seen as economical and truly desired (Doveton 1986).
According to the IPA Core analysis, the top three affected networks solely expressed in the low oxygen group were " Lipid Metabolism, Small Molecule Biochemistry, Dermatological Diseases and Conditions" (score 77), " Nucleic Acid Metabolism, Small Molecule Biochemistry, Organ Morphology" (score 33) and " Hereditary Disorder, Metabolic Disease, Cardiovascular Disease" (score 33).
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According to the N-clique analysis and M-core analysis, the majority of researchers are in low N-clique and M-core, which once again proved that the research collaboration in health management research is not tight.
Similar to previous study in oncology or cardiovascular field [ 44- 46], while in N-clique and M-core analysis, the frequency of 2- or 3-institutional collaboration is higher, which indicates that it is an irresistible trend that the scientific manpower of different institutions should be integrated.
Among the six networks identified by the core analysis using the IPA software, the top network (with 13 genes) confirmed previous data on the role of AR in CRPC.
Nevertheless, the proportion of drugs used was not statistically different, and the core analysis of the study was the longitudinal evaluation of autonomic function of each group, in which each subject served as his or her own control.
The 452 genes with a combined score of 2/−2 were used for the core analysis of the functions of the predicted target genes in Ingenuity Systems Pathway Analysis.
The results of the core analysis for the comparison of atf3 mutants (atf3a_1 and atf3a_2) against controls (yw_1 and yw_2) are provided as Additional files.
For the core analysis of the raw data, we have carefully selected the most appropriate previously published software programs.
As a further reminder, the core analysis reflects the basic contact network with Ferguson-like natural history of influenza, 90 percent compliance, rapid implementation (day after 10 cases diagnosed), restrictive rescinding (0 cases in 7 days) and regional mitigation.
Molecular networks are presented which were generated by the core analysis of the Ingenuity knowledge database (see also Methods section and www.ingenuity.com for explanation and details).
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