Sentence examples for core amplification from inspiring English sources

The chromosomal regions, 7F on chromosome X and 30B on chromosome 2L, are each represented by a single gene, sprite and Gdi respectively, in the core amplification regions.

Although their core amplification circuit exhibited impressive performance with a low uncatalyzed reaction rate as evaluated by a FRET-based output reporter, their Spinach aptamer output suffered low signal-to-noise ratio, and catalytic turnover was not explicitly demonstrated.

Although the most common pattern was for amplification of both cores, amplification of either core alone occurred in a minority of cancers.

We performed qRT-PCR for genes in the core 8p11-12 amplinicatiourin our experimentally amplified clones (Fig.  5).

Taken together, these results suggest that, in a significant proportion of cases with core A2 amplification, FGFR1 may be the actual amplicon driver [ 6].

In that work, they designed a core signal amplification circuit in which hybridization of two DNA hairpins (H1 and H2) was catalytically triggered by an input.

Evidence that this simplified model is incorrect emerged from high-resolution comparative genomic hybridisation analysis of breast cancer suggesting two major cores, or peaks, of amplification (core A1 distal at 36.5 to 37.8 Mb, and core A2 proximal at 38.1 to 38.9 Mb; Genome Build 35) [ 41].

The target genes driving the 11q13 amplicon have been extensively reported, and at least four cores of amplification have been established in breast cancer [ 33, 34].

Recent data using BAC-based array-CGH on independent sets of breast tumours have confirmed the frequent nature of gains on chromosome 1, as well as the existence of multiple cores of amplification (Stange et al, 2006).

Closer inspection of the Q-values in this region reveals three narrow peaks (Fig. 5a), which is in line with previous findings of three cores of amplification in this region [ 39].

Another study confirmed amplifications of 11 genes in 11q13, and found two amplification cores, including core 1 (TPCN2 and MYEOV), and core 2 (from CCND1 to CTTN).