core alignment

USAGE SUMMARY

The phrase "core alignment" is correct and usable in written English.
It can be used in contexts related to organizational goals, personal values, or physical fitness, where it refers to the central or essential alignment of elements. Example: "Achieving core alignment between our team’s objectives and the company’s mission is crucial for our success."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

21 human-written examples

This yields an accurate core alignment by first aligning each database sequence to its most closely-related profile and then aligning each profile alignment to the structural core based on the (manually-curated) template alignment.

BMC Evolutionary Biology

A whole genome sequence alignment of the 12 C. trachomatis genomes was created using progressive Mauve [ 59, 60] and the core alignment was extracted by keeping only the regions where all genomes aligned over at least 500 bp.

Biology Direct

The damage zone of the GF is asymmetrical around the axes determined by the core alignment and almost exclusively concentrated south of these axes.

Earth, Planets and Space

We tally the results in this manner so as to perform a more reasonable comparison between the core alignment aspects in the context of the whole human genome of other methods.

Plosone

Mugsy also identified a slightly longer core alignment.

Bioinformatics

The resulting core alignment was used to infer a Maximum Likelihood tree with RAxML [ 59].

BMC Genomics

Human-verified similar examples from authoritative sources

Similar Expressions

39 human-written examples

About 1952 the first relatively cheap RAM was developed: magnetic core memory, an arrangement of tiny ferrite cores on a wire grid through which current could be directed to change individual core alignments.

Encyclopedia Britannica

The two trimmed core alignments were used for further phylogenetic analyses.

BMC Evolutionary Biology

Despite differences in the alignment, the phylogenetic trees based on the two core alignments produced identical topologies with similar Bayesian support values.

BMC Evolutionary Biology

Maximum-likelihood phylogenies for all 2,140 individual core alignments were constructed at both the DNA and protein level, using the same parameters as above.

Genome Biology and Evolution

In total, 1,000 bootstrapped replicates were made from each of the four core alignments using SeqBoot from Phylip with default settings.

Genome Biology and Evolution

Expert writing Tips

Best practice

When describing a "core alignment", be specific about what constitutes the "core". Define the criteria used to identify the essential elements being aligned for clarity and precision.

Common error

Avoid using the term "core alignment" without clearly defining what the "core" represents. If the core elements are not well-defined, the alignment might lack a clear purpose or meaning, leading to confusion.

Linguistic Context

The phrase "core alignment" functions primarily as a noun phrase, typically used as a subject, object, or complement within a sentence. As indicated by Ludwig AI, it signifies a fundamental matching process, frequently observed in scientific and technical writings.

Expression frequency: Common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

The phrase "core alignment" is a grammatically sound and commonly used term, predominantly found in scientific literature. It functions as a noun phrase, describing the alignment of essential elements, as confirmed by Ludwig AI. The primary purpose is to illustrate a comparison method in fields like genomics. Given its formal register and frequent occurrence in academic sources, using "core alignment" appropriately requires understanding its technical context. For alternative phrasing, consider "central alignment" or "essential alignment" for similar meanings.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

central alignment

Replaces "core" with "central", emphasizing the importance of the alignment being at the center.

essential alignment

Substitutes "core" with "essential", highlighting the necessity of the alignment.

primary alignment

Replaces "core" with "primary", focusing on the main or principal alignment.

fundamental alignment

Substitutes "core" with "fundamental", stressing the basic or foundational nature of the alignment.

main alignment

Replaces "core" with "main", indicating the most important alignment.

structural alignment

Changes the focus to the structure of the alignment instead of the core element.

backbone alignment

Replaces "core" with "backbone", drawing an analogy to a structural foundation.

key alignment

Substitutes "core" with "key", emphasizing the critical importance of the alignment.

principal alignment

Replaces "core" with "principal", suggesting a leading or foremost alignment.

critical alignment

Substitutes "core" with "critical", highlighting the crucial nature of the alignment.

FAQs

How is "core alignment" typically used in scientific research?

In scientific research, "core alignment" usually refers to the alignment of essential or highly conserved regions in biological sequences, such as DNA or protein. It's used to identify evolutionary relationships and conserved functional domains.

What are some alternatives to using "core alignment" in a sentence?

You can use alternatives like "central alignment", "essential alignment", or "fundamental alignment" depending on the specific context and emphasis you want to convey.

What tools are commonly used to perform "core alignment" in bioinformatics?

Common tools for performing "core alignment" in bioinformatics include MAFFT, MUSCLE, and ClustalW. These tools use algorithms to align conserved regions across multiple sequences.

How does "core alignment" contribute to phylogenetic analysis?

"Core alignment" is crucial for phylogenetic analysis because it focuses on the most conserved regions, which are less likely to be affected by noise and more likely to reflect true evolutionary relationships. This leads to more accurate phylogenetic trees.