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It was a long cord of human hair, a fishing line perhaps, wound around a small wooden board covered in hieroglyphic writing.
In 1868 the Bishop of Tahiti, Florentin-Étienne Jaussen, received a gift from recent converts on Easter Island: a long cord of human hair wound around a discarded rongorongo tablet.
To test the binding properties of the patient plasma filtrate and purified IgG, we used 20-µm frozen sections of brain and lumbar spinal cord of naive rats and, in addition, 20-µm frozen sections from frontal cortex, amygdala, and spinal cord of human control autopsy material without CNS disease.
Until recently, it was not possible to gain access to the cells affected in the spinal cord of human patients.
More importantly, tau inclusions in the spinal cord of human P301S tau transgenic mice were labelled following a single intravenous injection of FSB.
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In designing the present study, we wondered if an analogous subtraction process might occur in the dorsal horn of the spinal cord of humans.
Although generally not considered to have a clinical role compared with liver flukes, several intestinal FZTs can cause serious pathologic effects, even death, when infecting the heart, brain, and spinal cord of humans (1, 9, 11 ).
To gain insight into the significance of this mechanism in human FALS, we performed immunohistochemistry on spinal cord sections of human SOD1-linked FALS cases to examine co-localization of KAP3 and SOD1.
BPA has been also detected in follicular fluid, foetal serum, and amniotic fluid (average 1-2 ng/mL) [ 23] and in umbilical cord serum of human mid gestation embryos [ 24].
To investigate whether FSB was staining tau inclusions in the spinal cord of transgenic human P301S tau mice, we performed double labelling with anti-tau antibodies and FSB.
To address this issue, we evaluated the expression state of CCR2 as well as MCP-1 in the spinal cord of mutant human SOD1 transgenic mice, by quantitative and morphological approaches using a reverse transcription-quantitative polymerase chain reaction (RT-qPCR), immunohistochemistry, and immunoblotting techniques.
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