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In addition, increased levels of oxidative DNA damage were reported in the spinal cord of both sporadic and familial ALS patients21.
Transplant-derived cells showed robust long-term survival post-injection and efficiently differentiated into astrocytes in injured spinal cord of both immunesuppressed mice and rats.
We examined the effectivess of tamoxifen to induce recombination in the spinal cord of both Myrfwt/wt and Myrffl/fl mice heterozygous for the PDGFRα-CreERT2 and the Rosa26 mGFP (mT/mG) transgenes after injury.
In ALS, in the brainstem and spinal cord of both patient and animal models, increasingly large numbers of activated microglia and astrocytes, IgG, and T lymphocytes [13], [34] [36] may be capable of secreting the numerous cytokines playing key roles in the inflammatory reaction.
βgal activity in the spinal cord of both groups of AAV-treated GM1 mice was comparable at all time points analyzed at approximately 50% of enzymatic activity in HZ spinal cord (same observation as in the cerebellum of AAV-T GM1 mice).
HPLC analysis revealed a comparable age-related decline in the total amount of GlcCer in spinal cord of both SOD1(G86R) and WT mice (Fig. 3A).
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From their respective gadgets, the cords of both men ran over to one side of the room and then into a box equipped with lights - a red one for one man and a green one for the other - and buzzers.
To uncover the physics of roaring, Dr. Titze and his colleagues built computer models of the vocal cords of both lions and tigers based on measurements of tissue samples taken from zoo animals that had been euthanized because of old age.
Reduced laminin labeling was observed in cervical and lumbar spinal cords of both early and late symptomatic G93A mice, possibly indicating vascularization changes leading to capillary wall permeability.
Aggrecan cleavage was readily detectable in injured spinal cords of both Adamts4−/− and Adamts5−/− mice.
The grey matter showed ischemic cell change in the spinal cords of both laminectomy and syrinx rats.
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