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The lower sequence divergence observed in the IRs rather than LSC and SSC regions for Phoebe species is likely due to copy correction between IR sequences by gene conversion (Khakhlova and Bock 2006).
However, copy correction between IR domains may contribute to genome stability- an especially important fact when one considers that an algal cell may contain hundreds of chloroplast DNA molecules [ 61].
The large inverted repeats in the chloroplast genome contain a combination of novel of intergenic spacer region structures and SNP variants when rDNA-containing domains are compared, indicating the possible loss of a copy correction mechanism.
The non-meiotic exchange of genetic information [ 5] between the major lineages may have occurred only twice in the entire history of the species [ 6, 7], although more regular exchange among close relatives may provide a unique form of intra-strain copy correction [ 7- 10].
Though speculative, the presence of alternative operon structure for the ribosomal genes, combined with the elevated appearance of SNPs suggest that the well-recognized "copy correction" mechanism [ 42] may be more effective in some "green" algal lineages (chlorophytic algae and algae with chlorophytic algal symbionts), than in the "red" lineage of autotrophs (rhodophytes and CASH taxa).
This could be explained by nonallelic homologous recombination among the GC42 sequences, by purifying selection acting on gene synonymous sites (Lawrie et al. 2013), and/or by targeted copy correction by gene conversion on protein coding genes (Khakhlova and Bock 2006; Christensen 2013).
Similar(54)
When the re-afference differs from the efference copy, corrections have to be made so as to bring the present pattern of movement back to the original image left in the brain.
Except for minor copy corrections, the following is his unedited essay in its entirety.
The direct repeats may have a recent evolutionary origin, frequently conduct copy corrections, and are of significant functional relevance.
The highly conserved stem-loop structure detected among the Vandenboschia and Equisetum repeats suggests that the repeats should potentially have a recent evolutionary origin, frequent copy corrections, and certain functional roles.
A key component of WaveCNV is the matched normal-based copy numatched normal-based
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