They worried about issues such as whether to charge for access to their sites; whether to put up all their content, for fear of seeing their print sales cannibalised; whether to increase their staff to update their copy more often; how to charge for advertising.There were some clear advantages to publishing on the Internet.
(i) According to the generation time hypothesis, species with shorter generation times are expected to have higher substitution rates because their genomes are copied more often per time unit [ 109].
Indeed, X TE copies are more often in a position to produce an effective repressor, because they are transmitted to the offspring via the oocyte cytoplasm.
Now, copying is more often a way of disseminating music that isn't receiving saturation exposure from MTV and radio stations: rarities, out-of-print music, things that stores and recording companies haven't made widely available.
In molecular evolution, generation time (T) is expected to be one of the primary determinants of the substitution rate of neutral mutations per time-unit, because species with short T copy their genomes more often, accruing more copy errors per year [ 1, 2].
There are also euchromatic copies of TEs which are more often complete copies and potentially actively transposing.
It is also not clear, she said, why other painters have not copied the effect more often.
However, we found copy neutral LOH was much more common in samples with a p16 mutation (7/8, 87.5%) than in samples without a p16 mutation (20/45, 44.4%) (p = 0.05), and that p16 mutation was found in samples with copy neutral LOH significantly more often than with copy loss LOH (7/27 vs 1/26, p = 0.05).
Compared to female breast cancers, EGFR (p = 0.005) and CCND1 (p = 0.041) copy number gain was more often seen in male breast cancer, while copy number gain of EMSY (p = 0.004) and CPD (p = 0.001) and amplification in general was less frequent.
This finding is in agreement with different studies indicating that strains with a high number of IS 6110 copies have lost genomic regions more often than strains with only few copies [ 10, 22].
