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When copies have a 90° or 270° rotation, Kim's method fails to discover them.
Patients with two copies have a 15-fold risk increase.
Although the latter case concerns a bacterial transposase, it is unlikely that its duplication in yeast results from its activity because no polymorphism is observed among the tested strains, and two copies have a mutation in the catalytic domain.
For example, species 7, 8, 15 and 16 when given 20 copies have a state-space size of 231.
In ATon-II, 83 elements have sequences identical to the consensus sequence and 166 copies have a divergence value ≤ 1%.
However the transcripts for these copies have a low to medium expression level, which means that high k-mer values are not appropriate.
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Additionally, the L. braziliensis chromosome 21 and 8 copies have an aspartic acid to glutamic acid replacement at position 437.
However, Kim's method can only detect copies having a 180° rotation.
Of course, any video game series that sells 40 million copies has a guaranteed audience waiting to see each movie version.
I.e., each of the two copies had a 50% chance of surviving.
Furthermore, most BuT5 copies had a size similar to that of the original BuT5-1 copy (∼1 kb) or were smaller (partial copies).
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