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In 1997 it began selling a caching server, which delivers Web pages ten times faster by storing page copies close to the user's computer.
The detachment of the dual action ligand from the receptor is more likely to be followed by re-attachment if there are GRPR binding copies close to it, resulting in higher receptor affinity for homodimers and better tumor uptake with longer tumor retention [26].
A closer inspection, however, reveals that 3 of them have exact copies close to each other.
Upregulation and downregulation were determined as significant (P value <0.05) Mann–Whitney comparisons of the expression of each driver TF in samples with deletions –or amplifications – to samples with a number of copies close to normal (between –0.75 and 1).
In the genome of D. simulans, most of the activity track distributions were bimodal, with few TE copies close to 1 and a large number of copies close to 0 corresponding to old and degraded copies (supplementary fig. S3, Supplementary Material online), which was consistent with the observations made for some of these TE families in the genome of D. simulans (Lerat et al. 2011).
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An increase in the expression of the single X gene copy in the male brings the expression level closer to that of the two female copies and close to that of autosomes.
Several issues have sold more than one million copies; not close to Seventeen, the market leader at 2.6 million, but quite impressive for a start-up.
Some copies stick close to the original, and others riff more freely, but the best find a way to make their versions equally interesting in a different way.
The books have been translated into 30 languages and have sold more than 50m copies worldwide – close to 9m in the UK.
The 4DTV distance between F3'5'Hp and other F3'5'H copies is close to the peak of 4DTV distances between grape paleologues observed by Tang and coworkers [ 16].
It was not included in the analysis shown on Figure 3 and Figure 4 because, intriguingly, none of its three gene copies is close to the ones of P. chrysosporium or its other relatives.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com