Motor proteins such as dynein and kinesin transport cargoes along microtubules; each motor is composed of two identical copies of the protein bound to each other.
The human Crm1 interface was used to orient two copies of murine Crm1 bound to RanGTP by aligning murine Crm1 with the human Crm1 interface, which shows little deviation between Cα atoms.
The six chimps, just pounding away at the typewriter keys, would be bound to copy out all the books ever written by man.
Cubist painters were not bound to copying form, texture, colour, and space; instead, they presented a new reality in paintings that depicted radically fragmented objects.
Ultimately, we have a high-profile couple, shot by a high-profile photographer – a combination that is bound to shift copies.
In total we could locate in the asymmetric unit 12 copies of RBP SH3-II bound to Aplip1-PxxP1.
The 26S proteasome consists of a core 20S particle, which contains the catalytic proteinase functions, symmetrically bound to two copies of the regulatory 19S particle.
In the transactivator configuration, a chimaeric transactivator (cTA) protein, formed by the fusion of CymR with the activation domain of VP16, is able to activate transcription when bound to multiple copies of CuO, placed upstream of the CMV minimal promoter.
A typical SELEX round includes the following three steps: (i) binding, incubation of the library with the target; (ii) partitioning, separation of target-bound library sequences from unbound ones; and (iii) amplification, generation of a new pool of nucleic acids by making multiple copies of the sequences that bound to the target.
It's a great idea that's bound to be copied by others, as will some of the gadgets.
