Exact(2)
SHORT1 copies accumulated via a recombination-based mechanism in the common rodent ancestor of today's mice and rats.
It also shows that the number of copies accumulated in the genome is not useful for predicting the level of transcript production.
Similar(58)
The functional fate of the two (initially) identical gene copies originating from a duplication event depends on the further modifications (evolutionary divergence) that one (or both) of the two redundant copies accumulates during evolution.
Third, both copies accumulate mutations that alter the original function, but the original function is retained and compensated cooperatively.
Eventually, distinct gene copies accumulate differences, leading some of them to degenerate into pseudogenes [ 6].
From this point, copies accumulate mutations independently, and their divergence increases with time.
As well as perfectly transposed EhSINE1s, truncated copies are usually present while even complete copies accumulate indels.
Notably, Sireviruses currently take up ~21% of the maize genome and ~90% of the maize Copia population, with the majority of copies accumulating during the last 600,000 years [ 24].
Theory and empirical evidence suggest that these duplicate copies accumulate on the autosomes (Connallon and Clark 2011; Gallach and Betrán 2011).
Afterward, most of the copies accumulate stochastic mutations and are lost over time by attrition, except for a minority of copies that can become exapted and can be identified as DNA segments conserved across species (Margulies et al. 2003; Siepel et al. 2005; Pace et al. 2008).
Furthermore, it would be expected that competition with highly expressed ta-TRIM elements could drive the extinction of an autonomous retrotransposon group such as lennie, as the rate of their own retrotransposition decreases and the existing copies accumulate deleterious substitutions (Schulman 2012).
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