Without life-size copies, we are the blind leading the blind.
An in-house memo noted "if we can't sell 15 to 20 thousand copies we ought to be shot".
To reduce bias due to random distribution of reads across TE copies we considered TEs as metagenes that describe the entire set of TE copies across the genome.
If we'd known it was going to sell millions of copies, we might have spent a bit more time thinking about every little detail," he tells me.
"When we took the decision to offer pick-up as well as paid-for copies, we made a commitment to advertisers to maintain the readership of the paper," he added.
This year, he said, "It was counted differently, because we had a postal inspector come in and tell us the copies we were dropping off at community centers could not be counted as part of our newsstand numbers".
Our algorithm strictly generalizes previous adaptive caching algorithms for exact copies: we can set parameters to require that all approximations be exact, in which case our algorithm dynamically chooses whether or not to cache each data value.
The more copies we can sell, the better.
In the U.S., two-thirds of copies we put out often come back unsold.
For a set of famous artworks, we downloaded all the plausible copies we could find.
To demonstrate the presence of integrated transgene copies, we further investigated the fate of the transgene by DNA blot analysis.
