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These key attributes of holonic manufacturing system (HMS), such as robustness when faced with perturbation, autonomous, cooperation and coordination were tested and validated in this open and distributed environment.
The effects of VU0467154 on motor coordination were tested using a rotarod (model 4600, Ugo Basile, Comerio, Italy) with a rod diameter of 3 cm.
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Sensory-motor coordination was tested using balance beams (45 cm length; 30% incline).
Motor coordination was tested on the rotarod apparatus as described previously [ 34, 35].
Motor coordination was tested as described in Gonzalez-Usano et al. (17) with a wood strip (20-mm diameter).
Coordination was tested by asking the children to stand 10 seconds on each leg, once with eyes open and once with eyes closed [ 25].
Animal coordination was tested on an 11 mm diameter and 50 cm long horizontal wooden rod at 4, 6, 9 and 12 months of age.
To test for dynamic motor behavior and locomotor coordination, animals were tested on an accelerating RotoRod device (IITC Instruments, CA, USA).
Thus, two initial coordination numbers (CN) were tested for U VI): the first with CN=8 and the second with CN=10.
Motor coordination and balance were tested using the rotarod test.
To determine if the reduction in enzymatic capacity translated to a physical abnormality in coordination, heterozygous mice were tested by rotorod.
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