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Although there is no shortage of acidic residues for calcium coordination in the second EF hand (consider the neighboring Asp73, Glu74, Asp75, Asp79, and Glu84), the reduction of the negative charge might reduce affinity of this site for calcium.
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As minister of planning and economic coordination in the first three years of the dictatorship, he helped create the Central Bank, reform the tax system and organize a workers' benefits system and a national housing bank.
In each of the complexes 3, 4 and 5, cadmium II) is coordinated meridionally by a depronated terdentate Schiff base {(L1)− for 3 and (L2)− for 4 and 5} and two nitrogen atoms of the (PRTZ)− in 3 and 4 and two nitrogen atoms of the (PZTZ)− in 5. Water molecules coordinate in the sixth coordination sites of cadmium II) in the complexes to complete their distorted octahedral geometries.
In the present work, both bargaining parties select their coordination strategy in the first stages.
JP participated in the coordination on the second research site.
In particular, the two bridging aspartates Asp90 and Asp188 (and121 Asp226p226 in UlaG) adopt rotamers that bring the carboxylates closer to the Mn2+ (site Zn2) ion by 0.6-1 Å, and two histidine residues in the coordination sphere of the second Mn2+ in the B. melitensis enzyme (site Zn1) are either in a distinct conformation (His88, His119 in UlaG) or have no equivalent in UlaG (His170).
PSH conceived the study, and participated in its design and coordination, reviewed the second round of analysis, and helped to draft the manuscript.
Whereas not all work in Phase 1 focused on care coordination, in a second phase, the four sites selected to continue emphasized care coordination activities.
This proposal is based on the design of an educational project dealing with the horizontal coordination of subjects taught in the second year of the Bachelor's Degree in Primary School Education at the Universitat Jaume I in Castellón, Spain.
All isotopic substitutions, changes in stereoconfiguration, tautomeric state and coordination bonding are reflected in the second block.
Improvements in coordination have been completed in the second phase of the program, and as a part of the strategy of the NRHM.
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