A spokesman for the International Paralympic Committee IPCC) said: "Although we are sympathetic with Bethany's view, we would like to stress that the 30s classes are not and never have been just for athletes with cerebral palsy but athletes with coordination impairments.
A subgroup of patients with acute to subacute low back pain (LBP) presenting with trunk movement control deficits, pain provocation with segmental testing, and segmental hypermobility have been clinically identified as having movement coordination impairments (MCIs) of the trunk.
2) Two of the most pronounced phenotypes reported in MeCP2 overexpression in mice are context dependent fear conditioning and motor coordination impairments on the rotating rod (Collins et al., 2004; Na et al., 2013, which should also be cited).
The aim of this study was to evaluate the presence of motor coordination impairment in a population of children affected by MoA, and its role as putative risk factor for motor skills impairment.
The exclusion criteria were: volunteers affected by vascular and/or neurological systemic conditions, presence of other concomitant headache, movement coordination impairment or any musculoskeletal disability that could interfere in the test performance.
For the analysis of game usability, the participant was a 7-year-old girl with cerebral palsy, speech disorder, motor coordination impairment, quadriplegic, and a dependent level in ADL according to the evaluation of Matsukura and Marturano (2001).
For the analysis of the effectiveness of the digital game, the participant was a 5-year-old boy with cerebral palsy, speech disorder (dysarthria), motor coordination impairment, and a semi-independent level in ADL according to the evaluation of Matsukura and Marturano (2001).
We thus asked whether unilaterally infusing N-SYN into the SNpc everyday for two weeks causes motor coordination impairment.
Deficiency in both P-Rex1 and P-Rex2 does not disrupt Purkinje cell dendrite morphology further, but causes more severe motor defects, with gait and posture abnormalities as well as motor coordination impairment [21].
These findings led to the hypothesis that the major motor coordination impairment observed in BK−/− mice results from a decreased net inhibition of deep cerebellar nuclei by the PCs [7].
The lower simple spike firing rate in BK−/− PCs, or the lower complex spike firing rate and longer subsequent pause do not account for the severe ataxic phenotype of mutants, since similar abnormalities in simple and complex spike firing have been described in other mouse models with mild or absent motor coordination impairment [43].
