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In addition to progressing our understanding of cystic pathophysiology, rodent models of cystic kidney disease have played a major role in facilitating the molecular characterization of novel genes required for normal renal epithelial cell function [ 10, 11] and establishing the importance of the ciliary-centrosome interactions in coordinating many aspects of cell division [ 12].
We thank Jason Harless for coordinating many aspects of the feasibility study and all of the participants at the 2009 Dublin, Ireland, ICAPPO workshop who contributed their insights and ideas: I. Aguilera, F. Ballester, K. Belanger, M.-H.Chang, G. Collman, M. Dostal, K. Gray, C. Iñiguez, B.-M. Kim, K. Polanska, and J. Rankin.
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Circadian clocks allow plants to temporally coordinate many aspects of their biology with the diurnal cycle derived from the rotation of Earth on its axis.
BP conceived the study, coordinated many aspects of the study and contributed to the writing of the manuscript.
BP participated in the design of the study, coordinated many aspects of the study and wrote the manuscript.
Ubiquitous among invertebrates, pheromones are used to coordinate many aspects of social behaviour, including sexual recognition and attraction to bring opposite sex conspecifics together for mating [ 3].
It interacts with an array of partner proteins to coordinate many different aspects of DNA metabolism.
She was even chief of staff, a post that involved coordinating many Xerox functions.
This clock integrates temporal information and coordinates of many aspects of biology, including basic metabolism, hormone signaling and responses, and responses to biotic and abiotic stress, making clocks central to "systems biology".
The coordinator's role may be viewed as that of coordinating the program (or education process) and/or as supporting the coordination of the many aspects of self-management in the continuum of diabetes and related conditions when feasible (42– 42).
This definition covers many aspects of coordination.
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