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Transcription by RNA polymerase II and pre-mRNA processing are coordinated within the nucleus [ 39].
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The movement of Kinesin and Dynein motors in a coordinated manner causes the nucleus to move in a specific direction.
A large body of work has proved that transcription by RNA polymerase II and pre-mRNA processing are coordinated events within the cell nucleus.
Importantly, the replication timing profile of the genome is a dynamic, developmentally regulated feature that is coordinated with the reprogramming of gene expression and repositioning of chromosome domains within the nucleus [ 45, 46, 51].
A center weighted by the signal intensity within the nucleus was determined according to equation 1, where Xi is the coordinate of each pixel, and Si the signal intensity of each pixel.
Chromosome Human DNA is stored in 23 pairs of chromosomes within the nucleus of each cell.
It is important to note that the signal within the cytoplasm and nucleus is obtained by an unbiased preset-analysis tool within the AMNIS analysis software, where a mask is created within the nucleus and the mean pixel intensity of β-catenin within the nucleus is compared to that within the entire cell (nucleus+cytoplasm).
Graphs reveal a histogram of standard deviation (SD) of fluorescence distribution within the nucleus.
Thresholded images were counted for positive foci within the nucleus of NeuN-positive neurons.
Within the nucleus, although not shown here, are the chromosomes which carry DNA.
Normally, a cell transcribes its genes into messenger RNA (mRNA) templates within the nucleus.
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