Sentence examples for coordinated modifications of from inspiring English sources
Taken together our data suggest that genome-wide coordinated modifications of histone acetylation (i.e. H3K9, H3K14 and H3K27) and methylation (H3K4me3) provide a general signature for facilitating gene expression over active promoters.
This leads to a model whereby Pkc1 promotes the coordinate modification of these two chromatin modifications and H3T45 phosphorylation is functionally coupled to H3K56 acetylation.
This bifunctional character of HOTAIR could be required for coordinating histone modifications of H3K27 methylation and H3K4 demethylation for epigenetic gene silencing in the metastatic processes.
Often, the Euclidean distance between two color coordinate points (or modifications of this distance) is used to express the difference between the colors associated with these points.
Examples of such interventions can include the funding of specific initiatives by local health authorities, development of specific organizational projects under the impetus of coordinating bodies or modification of relationships between organizations because of restructuring services at various levels of Local Centres and Networks.
Our results suggest that specific changes in histone modifications coordinate the regulation of genes and pathways involved in EMT.
This way the team of developers were able to receive suggestions and indications from users in various countries, coordinating the modifications and improvements to the software.
The results suggest coordinated action of different XTHs in cell-wall modification of xyloglucan moieties during flower opening as well as cell separation during abscission.
Post-translational modifications of the CTD coordinate the transcription cycle and various steps of mRNA maturation.
Establishment of specific epigenetic signatures within the cell requires coordinated action of numerous enzymatic machineries responsible for deposition (writers) and removal (erasers) of epigenetic modifications, as well as protein complexes that recognize these modifications (readers).
Regardless of the mechanisms underlying cis-regulatory modifications, however, coordinated changes in cis-regulatory elements can have a substantial impact upon the organism.
