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More complicated phenomena can be represented as the combined or coordinated effects of gain and loss of function.
It is now clear that the coordinated effects of multiple growth factors are needed to direct wound closure in order to avoid undesirable responses such as keloid formation and scarring [39].
The coordinated effects of PACAP and hMSCs on the increase of phagocytic microglia population and astrocytic glutamate uptaking ability may play the critical role in the promotion of spinal cord tissue repair and hindlimb recovery in rats with severe SCI.
Songbird studies further suggest that coordinated effects of FOXP2 and FOXP1 are relevant for spoken language.
The trade-offs in North Carolina resulted from the coordinated effects of several QTL regions on vegetative growth patterns and multiple components of reproductive output.
Finally, in the retrotransposon group, we discover the coordinated effects of 17 retrotransposon insertions on the resulting expression signal for retrotransposons.
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Uniquely, GLP-1R agonists exert coordinated effects on mechanisms of glucose release and nutrient uptake, suppress inappropriately elevated glucagon secretion, slow gastric emptying, and increase satiety with the net result of reduced body weight [ 2].
Overall, the coordinate effects of Rab25 mutation on AKT binding and ATP levels, glycogen content and glucose uptake suggests that the ability of Rab25 to bind and regulate AKT plays a critical role in the ability of Rab25 to regulate cellular bioenergetics, a contention supported by the PI3K, AKT and GSK3 inhibitor studies.
Every agent has an individual representation of the environment, and they are related through the coordinating effect of communication between agents with partial autonomy.
Multivariate comparison of the coordinate effect of the protease genotypes, as well as analysis of the effect of clinical features as covariants, was done with stepwise backward logistic regression analysis.
One way to coordinate the effects of CXCL12 signaling in the various CXCR4-expressing cell types is to exploit tissue-specific intracellular signaling pathways.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com