Sentence examples for coordinated down from inspiring English sources
Pathogen spreading is inhibited by hypersensitive response and cell death requiring coordinated down regulation of ROS-scavenging mechanisms (Apel and Hirt [2004]).
Our results revealed coordinated down regulation of genes involved in amino acid catabolism and transaminase activity during hibernation.
A major finding of this work is the coordinated down regulation of many oxidative phosphorylation and protein synthesis machinery genes with age in monocytes.
A cDNA microarray chip assay revealed coordinated down regulation of genes encoding enzymes of the cuticular wax biosynthetic pathway in the glossy mutant, with BnCER1 being one of the most severely suppressed genes.
Several waves of coordinated down- or upregulation in the expression of large gene clusters have been detected throughout the life cycle of Drosophila using microarrays technology [ 15, 16, 30].
Coordinated down regulation of cellular respiration genes in the liver, which plays the central role in metabolic homeostasis is consistent with the reduction of metabolic rate 20-500%) in hibernating bears.
The process of coordinated down-frequency regulation can be described as follows.
Microarray genes coding for structural myocardial proteins showed coordinated down-regulation in fish reared at 19��C compared to 14°C at both time points (Table 2), including different transcripts for myosin, actin and troponin.
Several groups of immune genes showed highly coordinated down-regulation with cortisol; genes involved in lymphocyte differentiation were equally suppressed by all treatments while two of the gene groups (antigen presentation and B-cell group) also responded to lice but at a much lower level.
Impaired bioenergetics with global down-regulation of mitochondria-related genes was the most predominantly conserved theme of neurodegeneration, accompanied by evidence of neuroinflammation, protein mishandling, oxidative stress, microglial activation, gliosis, and coordinated down-regulation of a host of genes essential for neurotransmission and normal neuronal function.
By repeatedly viewing its targets over five years, it should get to know the brightest stars' coordinates down to an error of just seven micro-arcseconds.
