Suggestions(1)
Exact(3)
In view of these small differences, we subsequently evaluated whether coordinated differences in genes belonging to a single biological pathway existed rather than differences in the expression levels of single genes.
As it is unclear whether large differences in the expression of a single gene are biologically more relevant than more subtle, although coordinated, differences in a set of genes belonging to a single biological pathway, we performed gene set enrichment analysis.
22 GSEA is designed to detect coordinated differences in expression of predefined sets of functionally related genes.
Similar(57)
Analysis at the single gene level may also miss small but coordinated expression differences in a larger number of genes that could belong to important biological pathways.
Although open field behaviour revealed no changes in locomotor function (measured in terms of distance travelled) due to enrichment, it is possible that this measurement alone does not have the sensitivity to reveal differences in coordinated motor activity between the two groups at the age tested.
The gender differences in coordinated stability remained significant after adjusting for height.
Once age and cognition were combined within the same model, the between-gender differences in coordinated stability in unadjusted analyses were no longer statistically significant at any time point (Table 4).
As there were no between-gender differences in coordinated stability at baseline and as the 4-week between-gender differences were evident after adjustment for baseline performance these results suggest that men may recover more quickly in the early stages of an exercise program.
It has been suggested that the role of the metal ion is to activate the respective carbon for nucleophilic ring closure via Lewis acid interactions with the coordinated oxygen moiety and consequently that differences in substrate coordination geometries in Ni II -ARD aNi II -ARDand may determine the respective catalytic route [135].
Superimposed on the many coordinated changes are prominence-specific differences in the expression of genes encoding transcription factors, extracellular matrix components, and signaling molecules.
Interindividual variability in stress resilience results from differences in the coordinated stress response.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com