Exact(5)
On the other hand, large groups of cells often undergo coordinated death during development and under conditions of severe tissue injury (Glucksmann, 1951; Jacobson et al., 1997).
Recently Drosophila HIPK has shown to be involved in a communal form of cell death, sudden, coordinated death among a community of cells without final engulfment step [35].
Finally, we examined whether AiA also occurs in vertebrates and whether it plays a physiological role for the coordinated death of groups of cells.
Inhibition of TNF-α disrupts the coordinated death of HF cells in catagen, indicating that this mechanism plays a physiological role to maintain synchronicity in the HF cycle.
On the one hand, there are situations where propagation of an apoptotic stimulus may be a useful mechanism to achieve the rapid and coordinated death of large cell populations.
Similar(55)
"There is no impediment to seeking the death penalty in New York," said Sean M. Byrne, executive director of the New York Prosecutors Training Institute, which coordinates death penalty issues for the state's district attorneys.
An official with the city's Law Department who has been coordinating death certificate applications on behalf of victims' families said she expected the final number of dead at the trade center to be between 3,000 and 3,700.
And down the corridor, as many as 40 people were jammed into a conference room, coordinating death certificates and fielding frantic calls from family members, while also trying to control the overflow of vital information.
Our results suggest that AiA and at least some of the underlying mechanism have been conserved in evolution to promote coordinated cell death.
The production of new hairs involves a cycle of growth, coordinated cell death (known as the catagen phase) and rest, and TNF-α signalling has been implicated in this cycle.
Mitochondrial dysfunction plays a causal role in neuronal cell death, as damaged mitochondria cause cell injury and coordinate cell death.
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