Sentence examples for coordinated cellular response from inspiring English sources
p53 is a critical nodal point of converging pathways from diverse cellular insults which can elicit coordinated cellular response that result in adaptation to the insult (Prives and Hall, 1999; Bates and Vousden, 1996).
The mitogen-activated kinases JNK1/2/3 are key enzymes in signaling modules that transduce and integrate extracellular stimuli into coordinated cellular response.
Cell migration is a highly dynamic process during which numerous signals must be integrated to generate a coordinated cellular response.
RecA and the SOS transcriptional repressor LexA are the two main proteins involved in this coordinated cellular response to UV-light and DNA-damaging agents [46].
A coordinated cellular response will require crosstalk between mitochondria and their cellular environment.
The coordinated cellular response to hypoxic stress in conjunction with the damage-potentiating role of oxygen following IR may largely explain the classic finding of hypoxic radioresistance.
The tools described here for understanding network motifs and their dose response properties should also be amenable to analysis of integrated networks in which groups of motifs work together in parallel or sequential patterns to control coordinated cellular responses.
Cancer metastasis is a complex process involving the coordinated cellular responses of both cancer cells and normal cells; invasion of the stroma, intravasation of the blood vessel, circulation in the blood, lodging and adhesion in the target capillaries, extravasation from the blood vessels and proliferation of secondary tumors [ 18].
ATM is a biosensor that coordinates cellular response to various damaging signals to preserve genomic integrity [ 8, 9, 22, 23].
UPR signaling pathways coordinate cellular response by down-regulating protein translation, enhancing expression of ER chaperone proteins that promote protein refolding, and activating proteases involved in the degradation of misfolded proteins.
Hannun, Y. A. Functions of ceramide in coordinating cellular responses to stress.
