Sentence examples for coordinate the progression from inspiring English sources

Under DNA replication stress, activation of the Cds1-dependent DNA replication checkpoint suppresses expression of the meiosis-specific transcription factor Mei4 and maintains the inactive state of CDK through Mik1/Wee1 to coordinate the progression of meiosis.

To ensure the fidelity and coordinate the progression of DNA replication, this challenging process is regulated by a DNA damage response network that includes S-phase checkpoints that sense stalled replication forks and DNA damage and facilitate DNA repair processes (Harper and Elledge 2007).

Here we propose a model in which the Cds1-dependent DNA replication checkpoint coordinates the progression of meiosis through Mei4-mediated and CDK-mediated regulatory pathways (Fig. 7).

The APC/C is a macromolecular E3 ubiquitin ligase that coordinates the progression of eukaryotic cells through mitosis, by the timely and selective targeting of protein substrates for 26S proteasome-mediated degradation through ubiquitylation (Harper et al, 2002; Peters, 2002).

Various plant hormones coordinate the initiation and progression of these processes, with abscisic acid (ABA) playing a central role (reviewed in [ 7, 8]).

Although aberrant expression of Wnt signalling has been well documented in various cancers, the exact molecular mechanism by which the dysregulated Wnt signalling and its down-stream targets coordinate the transformation and metastatic progression is as yet poorly understood.

During the DDR, Tel1 and Mec1 coordinate the halt of cell cycle progression with the activation of DNA repair mechanisms.

Interestingly, in Drosophila the onset of let-7 expression is temporally regulated by hormonal signalling and is coordinated with the progression to the adult state (Sempere et al, 2002, 2003; Bashirullah et al, 2003).

Notably, cellular differentiation is coordinated with the progression of cell cycle in the parental cell in all these yeast-mating systems, a feature likely to be very important in biology at large.

The mechanisms that coordinate the termination of DNA replication with progression through mitosis are not completely understood.

Wang, Q. et al. Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.